在纽约的“居家禁令”实施近一个月之后,州长安德鲁·科莫在周三的每日冠状病毒简报会上提出了几个让该州向“分阶段重新开放”过渡的方法。
在缺乏疫苗来预防这种疾病的情况下,库莫承认这种疾病可能需要12到18个月的试验才能获得,州长回顾了三种医学治疗方法,他说这些方法可能会促使COVID-19爆发的“自然终结”。除了作为冠状病毒管理疗法被广泛争论的羟氯喹,他还列举了两种可能性:抗体检测和恢复期血浆。
美国食品和药物管理局(FDA)还没有批准任何广泛用于冠状病毒患者的治疗方案。然而,该机构确实发布了初步准则周一,对于目前正在研究恢复期血浆有效性的医疗保健提供者和研究人员来说,抗体转移技术使用以前被感染的人的血液来治疗现在的病人。这种方法在历史上曾被用于各种疾病的爆发,包括流行性腮腺炎、麻疹和流行性感冒,尽管它在对抗COVID-19方面的成功尚未得到证实。
在最近的指南中,美国食品和药物管理局将恢复期血浆作为冠状病毒治疗策略的使用限制在随机临床试验,尽管它为“严重或立即威胁生命的COVID-19感染”的患者提供了津贴在这种情况下,医生可以向食品和药物管理局提交个人化的请求,以扩大获取途径。
纽约市已经在进行临床试验,以测试治疗方案的有效性,该市西奈山医院系统的研究人员和临床医生已经提出了要求疗养血浆捐赠潜在地帮助危重病人和研究结果。
3月30日,州长安德鲁·科莫在曼哈顿雅各布·贾维茨会议中心的新闻发布会上谈到了纽约的冠状病毒大流行。他每天举行简报会,讨论该州最新的COVID-19更新。
在周三的简报会上,科莫还宣布,纽约开发了抗体测试确定已经感染冠状病毒的卫生保健专业人员和其他重要工作人员。他说,该州计划从本周开始每天进行2000次检测,并已要求食品和药物管理局加快批准评估,以扩大准入。
关于冠状病毒疫苗的开发,科莫说,“越快越好。”他强调纽约迫切希望尽可能协助测试过程。
“我们会尽一切努力与联邦政府合作,让疫苗更快完成,我们都参与其中。你想把纽约州作为实验室吗?我们准备好了,愿意并且有能力,”他表示。“无论纽约州卫生部如何与美国食品和药物管理局合作来缩短检测周期,我们都积极参与,充满活力,富有创造力,雄心勃勃。所以,我们会尽一切努力加速疫苗的研发。你需要一个地方来大量测试它吗?想想纽约。”
截至周三下午,纽约已经在全州范围内确认了203,377例新冠状病毒病例,以及11,586例死亡病例。科莫表示,自周二的简报会以来,已有752人死亡,此前一周多以来,单日死亡人数一直相当高。
WHAT IS CONVALESCENT PLASMA? GOVERNOR CUOMO DISCUSSES POSSIBLE MEDICAL TREATMENT AHEAD OF COVID-19 VACCINE
Nearly one month into New York's stay-at-home order, Governor Andrew Cuomo presented several approaches to transition the state toward a "phased reopening" during his daily coronavirus briefing on Wednesday.
In the absence of a vaccine to protect against the disease, which Cuomo acknowledged will likely require 12 to 18 months of trials before it becomes available, the governor reviewed three medical treatments that he said could prompt a "natural end" to the COVID-19 outbreak. In addition to hydroxychloroquine, which has been widely debated as a coronavirus management therapy, he cited two possibilities: antibody testing and convalescent plasma.
The Food and Drug Administration (FDA) has not approved any of the treatment options for widespread use in coronavirus patients. However, the agency did issue preliminary guidelines on Monday for healthcare providers and researchers currently investigating the effectiveness of convalescent plasma, an antibody transfer technique that uses blood from a previously infected person to cure a current patient. The method has been employed during various disease outbreaks throughout history, including mumps, measles and influenza, though its success in combating COVID-19 has not yet been proven.
In recent guidelines, the FDA limited use of convalescent plasma as a coronavirus treatment strategy to randomized clinical trials, though it offered allowances for patients with "serious or immediately life-threatening COVID-19 infections." In those cases, physicians can submit individualized requests to the FDA for expanded access.
Clinical trials to test the treatment options efficacy are already underway in New York City, where researchers and clinicians belonging to the city's Mount Sinai hospital system have asked for convalescent plasma donations to potentially help critically ill patients and study results.
Governor Andrew Cuomo addressed New York's coronavirus pandemic during a news conference at Manhattan's Jacob Javits Convention Center on March 30. He holds daily briefings to discuss the state's latest COVID-19 updates.
During Wednesday's briefing, Cuomo also announced that New York has developed an antibody test to identify health care professionals and other essential workers who have already contracted the coronavirus. He said the state plans to begin administering 2,000 tests per day starting this week and has asked the FDA for expedited approval of the assessment in an effort to expand access.
Regarding the development of a coronavirus vaccine, Cuomo said, "the sooner the better." He emphasized New York's eagerness to assist in the testing process however it can.
"Anything we can do to work with the federal government to get the vaccine done faster, we are all in. You want to use New York state as laboratory? We are ready, willing and able," he expressed. "Any way the New York State Department of Health can work with the FDA to reduce that testing period, we are all in and energized and creative and ambitious about it. So, anything we can do to accelerate that vaccine, we will do. You need a place to test it in large numbers? Think of New York."
As of Wednesday afternoon, New York had confirmed 203,377 cases of the new coronavirus statewide, as well as 11,586 deaths. Cuomo said 752 people had died since Tuesday's briefing, following more than a week of comparably high single-day fatality counts.